Thursday will be only Mayfield’s second time playing against the Bills and 2018 NFL Draft first-round classmate Josh Allen. The first came in November 2019, as Mayfield helped the Cleveland Browns to a 19-16 victory and surpassed Allen’s career total. Mayfield threw for 238 yards and two touchdowns on 26-of-38 passing with no interceptions, while Allen (22-for-41) had 266 yards, no TDs and no interceptions.
Mayfield, the No. 1 overall pick in the 2018 draft, has completed 133 of 204 passes for a career-best 65.2 completion percentage with eight touchdowns and four interceptions this season. However, those four picks have come in each of the last four games. Mayfield and the Bucs offense have allowed 13 or fewer points in three of their last four games — all of which have resulted in losses. In those three losses, Mayfield has thrown just two touchdowns and three interceptions.